MEDICINAL PLANTS AS ALTERNATIVE ANTI-WEEVIL AND ANTIMICROBIAL AGENTS: A STUDY ON GLINUS LOTOIDES AND CROTON MACROSTACHYUS AGAINST SELECTED TEST ORGANISMS

*Gemechu Duguma Argessa

ABSTRACT

The rise of antibiotic resistance poses a global public health threat, necessitating the search for alternative anti-weevils and antimicrobial agents. This study investigates the antibacterial and anti-weevil activities of Glinus lotoides (Metere) and Croton macrostachyus (Bissana) against Escherichia coli and Staphylococcus aureus. The antibacterial activity was evaluated using the agar well diffusion method, revealing significant inhibition zones. The highest antimicrobial effect was observed in methanol extracts of Croton macrostachyus. Additionally, anti-weevil properties were assessed, demonstrating promising insecticidal effects. The results support the medicinal use of these plants and indicate their potential as alternative antimicrobial agents.

Keywords:

Antibacterial activity, agar well diffusion, anti-weevil, Croton macrostachyus, Glinus lotoides.

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