IMPACT OF LIFESTYLE FACTORS ON PROCREATIVE POTENTIAL WITH ADVANCED PATERNAL AGE

*Huma Ashraf, Rukhshan Khurshid, Sana Asghar, Mansoor Sultan, Qurrat Shoaib Saqib

ABSTRACT

Objective: A cross sectional study was designed to find out the impact of lifestyle factors including Mediterranean diet on procreative potential with increase paternal age. Methods: A total of 60 male subjects were included in the study.  Subjects were divided into 2 groups.  Group A consisted of 30 study subjects (age 60-70 years). Group B consisted of 30 control subjects (age 30-50 years). The study was conducted in Gilgit, Baltistan from January 2020 to December 2020. Level of blood glucose was measured with an Auto-Analyzer. Levels of Sex hormone binding globulin, testosterone, Bio available testosterone, Luteinizing hormone and follicle stimulating hormone were measured with ELISA. Results: Mean age of study subjects was 68.33 years and of controls 40.88 years. BMI/waist circumference, dietary pattern was quite similar in both groups. However group A were physically active. Group B joined gym and had an active life style. Mean level of fasting blood sugar, LH and FSH were increased in study group A as compared to control group B. Levels of SHBG and total testosterone, were quite similar in both groups. Levels of bio available testosterone were decreased in group A as compared to group B. Conclusion: Study found good association among active life style and a well nourished diet with procreative potential with increased paternal age.

Keywords:

Age, male sexual hormones, active life style and well nourished diet.

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